I am the Pro-Vice-Chancellor for Research at the University of Cambridge. I am also the Professor of Biological Chemistry, and lead a research team in the Department of Chemistry, Lensfield Road. My research is focused on using fragment-based methods in drug discovery and chemical biology. In 1999, I co-founded Astex, which grew to become the world-leading company in fragment-based drug discovery. I also have research interests in developing microdroplets as a novel experimental platform and consequently cofounded Sphere Fluidics (2010) and Aqdot (2013). I have published over 260 papers and am an inventor on numerous patents. I was a founding director of Cambridge Enterprise. From 2013-2015 I was the first Director of Postdoctoral Affairs and oversaw the development of the Office of Postdoctoral Affairs in the University.